Abstract

Author(s): Carneiro, Letícia Barroso Vertulli1; Lacerda, Elisa Maria de Aquino2; Medeiros da Costa, Verônica3; Luiz Luescher, Jorge4; Fontes de Lima, Géssica Castor1; Berardo Szundy, Renata4; Padilha, Patrícia de Carvalho5

Background: In Type 1 Diabetes Mellitus (T1DM) patients, the risk factors for developing cardiovascular disease begin in childhood, rising the risk of early development of atherosclerosis lesions and accelerated progression of cardiovascular diseases throughout adulthood.

Methods: This was a cross-sectional study. All the patients who registered at the clinic until November/2011 were included in the study. The dependent variables were total cholesterol, HDL, LDL and triglycerides. The independent vaables were gender, age, disease duration, body mass index, glycated hemoglobin and type of prescribed meal plan. A model of logistic regression for each outcome was built and those associations were considered significant with p <0.05.

Results: 195 patients were included in the study, mean age 11.01 years (± 3.78), and 55.9% were males. The frequency of overweight was 36.7%. High cholesterol was found in 42.8% of the sample, 15.8% had inadequate HDL, 7.9% increased LDL, and 12.5% increased triglyceride. Male children were more likely to have elevated total cholesterol (OR 2.21, 95% CI: 1.16-4.20) and 54% less likely (OR 0.46, 95% CI: 0.23-0.92) to have high LDL. Regarding triglyceride, those with older age and with high glycated hemoglobin had a greater chance of hypertriglyceridemia (OR 1.53, 95% CI: 1.23-1.90 and OR 4.89, 95% CI: 1.45-16,52, respectively).

Conclusion: A high prevalence of dyslipidemia was found among children and adolescents with T1DM, indicating the need to defining define measures and strategies to promote healthy eating habits and lifestyle..